TB-500

TB-500 is a synthetic peptide fragment corresponding to the active region of thymosin beta-4, a 43-amino acid protein that is one of the most abundant intracellular peptides in mammalian cells. Specifically, TB-500 encompasses the actin-binding domain of thymosin beta-4, centered around the sequence LKKTETQ, which has been demonstrated to play a pivotal role in actin polymerization dynamics and cytoskeletal organization in cell biology research. The interaction of TB-500 with G-actin monomers provides researchers with a precise molecular tool for manipulating the actin polymerization equilibrium.